Comparative analysis of chicken Hoxb-4 regulation in transgenic mice
نویسندگان
چکیده
منابع مشابه
Comparative analysis of chicken Hoxb-4 regulation in transgenic mice
We cloned the chicken Hoxb-4 gene and performed in situ analysis to investigate conservation in patterns of expression between the chicken and mouse. The anterior boundaries of expression for both genes in segmented tissues, such as the hindbrain and paraxial mesoderm, map to the same rhombomere (r) (r6/r7) and somite (s) (s6/s7) limits, showing a direct correlation between expression of a spec...
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15 صفحه اولDevelopmental regulation of the chicken βB1-crystallin promoter in transgenic mice
The cis-elements responsible for the high-level, lens-specific expression of the chicken beta B1-crystallin gene were investigated by generating mice harboring beta B1-crystallin promoter/chloramphenicol acetyl transferase (CAT) transgenes. Deletion of promoter sequences -434/-153 and -152/-127 as well as site-directed mutagenesis of the PL1 (-116/-102) and Pl2 (-90/-76) elements significantly ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 1995
ISSN: 0925-4773
DOI: 10.1016/0925-4773(95)00423-8